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Publications.

Published

(2026)

Ruglass, L. M., Gette, J. A., Morgan-López, A. A., Ye, A., Smith, K. Z., Fitzpatrick, S., López-Castro, T., Saavedra, L. M., Norman, S. B., Killeen, T. K., Back, S. E., & Hien, D. A. (2026). Indirect effects of Seeking Safety plus sertraline on alcohol use: The mediating role of reductions in posttraumatic stress disorder symptom severity. Journal of Traumatic Stress, 39, 239–248. https://doi.org/10.1002/jts.70031 

(2025)

Blakey, S. M., Morgan-López, A. A., Kline, A. C., Shevorykin, A., Norman, S. B., Killeen, T. K., Back, S. E., Simpson, T. L., Saavedra, L. M., Petrakis, I. L., & Hien, D. A. (2025). Treatment for co-occurring posttraumatic stress disorder and substance use disorders among veterans and civilians: A test of causally moderated comparative effectiveness. Psychological Trauma. https://doi.org/10.1037/tra0002043

Campbell, A., Burlew, K., Guille, C., Haidamus, M., Hien, D. A., Killeen, T., Lofwall, M., Paschen-Wolff, M., Patten, C. A., Sugarman, D. E., Winhusen, J., Bakhireva, L., Loree, A., Mazel, S., & Greenfield, S. F. (2025). Gender-specific addiction research needed now more than ever: Reflections from 25 years of the NIDA Clinical Trials Network Gender Special Interest Group. Journal of Substance Use and Treatment.

Global Collaboration on Traumatic Stress FAIR Data Workgroup. (2025). How to find, re-use, and share data for broader impact: Practical tools and tips for FAIR data. Zenodo. https://doi.org/10.5281/zenodo.15689194

Hien, D. A., Gette, J., Bauer, A., Saraiya, T., Ruglass, L. M., Lopez-Castro, T., Piccirrillo, M., Ellys, R., Best, E., Blakey, S. M., Ebrahimi, C., Back, S. E., Killeen, T. K., Saavedra, L. M., Norman, S. B., & Morgan-López, A. A. (2025). How changes in posttraumatic stress disorder severity mediate substance use disorder severity during and after treatment for co-occurring PTSD and SUD: Results from Project Harmony. Addiction. https://doi.org/10.1111/add.70126

Morgan-López, A. A., Blakey, S. M., West, S. G., Fitzpatrick, S., Norman, S. B., Killeen, T. K., Back, S. E., Saavedra, L. M., Kline, A. C., Lopez-Castro, T., & Hien, D. A. (2025). A framework for estimating posttreatment moderation of treatment-by-dosage effects in individual-patient meta-analysis: An illustration using Project Harmony. Clinical Psychological Science. https://doi.org/10.1177/21677026251351276

O’Neil, M., de Haan, A., Sadeh, Y., Marsac, M. L., Kassam-Adams, N., Morgan-López, A., Hamblen, J., Clauss, K., & Hien, D. (2025). Advances, challenges, and future directions in trauma-related FAIR data efforts. Journal of Traumatic Stress. https://doi.org/10.1002/jts.70006

Lopez-Castro, T., Gette, J., Back, S. E., Blakey, S. M., Killeen, T., Morgan-López, A., Norman, S., Ruglass, L. M., Saavedra, L. M., McGovern, M., Petrakis, I., Sonne, S., Brady, K., & Hien, D. A. (in press). WHO Drinking Risk Level Reductions as Treatment Outcomes in PTSD and Substance Use Disorder Trials. Drug and Alcohol Dependence. https://doi.org/10.1016/j.drugalcdep.2025.112837

(2024)

Back, S. E., Jarnecke, A. M., Norman, S. B., Zaur, A. J., & Hien, D. A. (2024). State of the science: Treatment of comorbid PTSD and substance use disorders. Journal of Traumatic Stress. https://doi.org/10.1002/jts.23049

Hill, M. L., Kline, A. C., Saraiya, T. C., Gette, J., Ruglass, L. M., Norman, S. B., Back, S. E., Saavedra, L. M., Hien, D. A., & Morgan-López, A. A. (2024). Cannabis use and trauma-focused treatment for co-occurring PTSD and SUD: A meta-analysis of individual patient data. Journal of Anxiety Disorders. https://doi.org/10.1016/j.janxdis.2024.102827

Morgan-López, A. A., Saavedra, L. M., Prakash, K., West, S. G., & Hien, D. A. (2024). The hidden psychometric model underlying the DSM. Psychiatric Services. https://doi.org/10.1176/appi.ps.20230370

Hien, D. A., Papini, S., Saavedra, L. M., Bauer, A. G., Ruglass, L. M., Ebrahimi, C. T., Fitzpatrick, S., López-Castro, T., Norman, S. B., Killeen, T. K., Back, S. E., & Morgan-López, A. A. (2024). Project Harmony: A systematic review and network meta-analysis. Psychological Bulletin. https://doi.org/10.1037/bul0000409

(2023)

Saraiya, T. C., Back, S. E., Jarnecke, A. M., Blakey, S. M., Bauer, A. G., Brown, D. G., Ruglass, L. M., Killeen, T., & Hien, D. A. (2023). Sex and Gender Differences in Co-Occurring Alcohol Use Disorder and PTSD. Current Addiction Reports, 10(4), 617–627. https://doi.org/10.1007/s40429-023-00511-5

Morgan-López, A. A., Saavedra, L. M., Hien, D. A., Norman, S. B., Fitzpatrick, S. S., Ye, A., Killeen, T. K., Ruglass, L. M., Blakey, S. M., & Back, S. E. (2023). Differential symptom weighting in estimating empirical thresholds for underlying PTSD severity: Toward a “platinum” standard for diagnosis? International Journal of Methods in Psychiatric Research, 32(3), e1963. https://doi.org/10.1002/mpr.1963

Ruglass, L. M., Shevorykin, A., Zhao, Y., Killeen, T. K., Bauer, A. G., Morgan-López, A. A., Back, S. E., Fitzpatrick, S., López-Castro, T., Norman, S. B., Saavedra, L. M., & Hien, D. A. (2023). Self-report and urine drug screen concordance among women with co-occurring PTSD and substance use disorders participating in a clinical trial: Impact of drug type and participant characteristics. Drug and Alcohol Dependence, 244, 109769. https://doi.org/10.1016/j.drugalcdep.2023.109769

Hien, D. A., Morgan-Lopez, A. A., Saavedra, L. M., Ruglass, L. M., Ye, A., Lopez-Castro, T., Fitzpatrick, S., Killeen, T. K., Norman, S. B., Ebrahimi, C. T., & Back, S. E. (2023). Project Harmony: A Meta-Analysis With Individual Patient Data on Behavioral and Pharmacologic Trials for Comorbid Posttraumatic Stress and Alcohol or Other Drug Use Disorders. American Journal of Psychiatry, 180(2), 155-166. https://doi.org/10.1176/appi.ajp.22010071

(2022)

Morgan‐López, A. A., Hien, D. A., Saraiya, T. C., Saavedra, L. M., Norman, S. B., Killeen, T. K., Simpson, T. L., Fitzpatrick, S., Mills, K. L., Ruglass, L. M., Back, S. E., & López‐Castro, T. (2022). Estimating posttraumatic stress disorder severity in the presence of differential item functioning across populations, comorbidities, and interview measures: Introduction to Project Harmony. Journal of Traumatic Stress, 35(3), 926–940. https://doi.org/10.1002/jts.22800

Saavedra, L. M., Morgan-López, A. A., Back, S. E., Patel, S. V., Hien, D. A., Killeen, T. K., Norman, S. B., Fitzpatrick, S., Ebrahimi, C. T., & Ruglass, L. M. (2022). Measurement Error-Corrected Estimation of Clinically Significant Change Trajectories for Interventions Targeting Comorbid PTSD and SUDs in OEF/OIF Veterans. Behavior Therapy. https://doi.org/10.1016/j.beth.2022.04.007

(2021)

Hien, D. A., Fitzpatrick, S., Saavedra, L. M., Ebrahimi, C. T., Norman, S. B., Tripp, J., Ruglass, L. M., Lopez-Castro, T., Killeen, T. K., Back, S. E., & Morgan-López, A. A. (2021). What's in a name? A data-driven method to identify optimal psychotherapy classifications to advance treatment research on co-occurring PTSD and substance use disorders. European journal of psychotraumatology, 13(1), 2001191. https://doi.org/10.1080/20008198.2021.2001191

Saavedra, L. M., Morgan-López, A. A., Hien, D. A., López-Castro, T., Ruglass, L. M., Back, S. E., Fitzpatrick, S., Norman, S. B., Killeen, T. K., Ebrahimi, C. T., Hamblen, J., & CAST, the Consortium on Addictions, Stress and Trauma (2021). Evaluating treatments for posttraumatic stress disorder, alcohol and other drug use disorders using meta-analysis of individual patient data: Design and methodology of a virtual clinical trial. Contemporary clinical trials, 107, 106479. https://doi.org/10.1016/j.cct.2021.106479

Fitzpatrick, S. S., Morgan-López, A. A., Saraiya, T. C., Back, S. E., Killeen, T. K., Norman, S. B., López-Castro, T., Ruglass, L. M., Saavedra, L. M., & Hien, D. A. (2021). Graded response item response theory in scaling suicidal thoughts and behaviors among trauma-exposed women with substance use disorders. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 10.1037/adb0000757. Advance online publication. https://doi.org/10.1037/adb0000757

(2020)

Morgan-López, A. A., Killeen, T. K., Saavedra, L. M., Hien, D. A., Fitzpatrick, S., Ruglass, L. M., & Back, S. E. (2020). Crossover between diagnostic and empirical categorizations of full and subthreshold PTSD. Journal of Affective Disorders, 274, 832–840.  https://doi.org/10.1016/j.jad.2020.05.031

​Ruglass, L. M., Morgan-López, A. A., Saavedra, L. M., Hien, D. A., Fitzpatrick, S., Killeen, T. K., Back, S. E., & López-Castro, T. (2020). Measurement nonequivalence of the Clinician-Administered PTSD Scale by race/ethnicity: Implications for quantifying posttraumatic stress disorder severity. Psychological Assessment, 32(11), 1015–1027. https://doi.org/10.1037/pas0000943

​Saavedra, L.M., Morgan‐López, A.A., Hien, D.A., Killeen, T.K., Back, S.E., Ruglass, L.M., Fitzpatrick, S., Lopez‐Castro, T. (2020). Putting the Patient Back in Clinical Significance: Moderated Nonlinear Factor Analysis for Estimating Clinically Significant Change in Treatment for Posttraumatic Stress Disorder, Journal of Traumatic Stress. https://doi.org/10.1002/jts.22624

​Hien, D., Kropp, F., Wells, E.A., Campbell, A., Hatch-Maillette, M., Hodgkins, C., Killeen, T., Lopez-Castro, T., Morgan-Lopez, A., Ruglass, L.M. and Saavedra, L. (2020) The “Women and Trauma” study and its national impact on advancing trauma specific approaches in community substance use treatment and research. Journal of Substance Abuse Treatment, 112, 12-17. https://www.sciencedirect.com/science/article/pii/S0740547219305811


(2019)

Morgan-López, A.A., Saavedra, L.M., Hien, D.A., Killeen, T.K., Back, S.E., Ruglass, L.M., ... & Patock-Peckham, J.A. (2019). Estimation of equable scale scores and treatment outcomes from patient-and clinician-reported PTSD measures using item response theory calibration. Psychological Assessment, 32, 321-335. https://psycnet.apa.org/doiLanding?doi=10.1037%2Fpas0000789 

(2015)

Hien,  D.A., Campbell, A.N., Ruglass, L.M., Saavedra, L., Mathews, A.G., Kiriakos, G., Morgan-Lopez, A. (2015). Maximizing Effectiveness Trials in PTSD and SUD Through Secondary Analysis: Benefits and Limitations Using the National Institute on Drug Abuse Clinical Trials Network "Women and Trauma" Study as a Case Example.
 J Subst Abuse Treat, 56, 23-33. doi: 10.1016/j.jsat.2015.04.001. Epub 2015 Apr 7. PMID: 25907849; PMCID: PMC4519371.

Accepted

Under Review

Prakash, K., Morgan-López, A. A., Gette, J. A., Peck, K., Piccirillo, M., Saavedra, L. M., Back, S. E., Killeen, T. K., Norman, S. B., West, S. G., Hien, D. A., & CAST (revise & resubmit). “Impaired but now diagnosable?” A melding of analytic frameworks for incorporating symptom weighting in model-based classification of full and subthreshold PTSD. Journal of Traumatic Stress.

Sadeh, Y., Graham, L., Kapa, H., Ford, J. D., de Haan, A., Hien, D. A., Jensen, T., Landolt, M., Meiser-Stedman, R., Nixon, R., Nugent, N. R., Olff, M., Ormhaug, S., Saxe, G., & Kassam-Adams, N., and the Child Trauma Prevention and Treatment Data Archive Project (revise & resubmit). Building the framework for ongoing discovery: Coding practice elements in child trauma intervention studies: Child Trauma Prevention and Treatment (CTPT) Data Archive project. European Journal of Psychotraumatology. 

In Preparation

Bauer et al. (in preparation). CAPS + PCL-5 Psychometrics

Blakey, S.M., et al. (in preparation) Can Clinician-Rated PTSD Severity be Estimated From Self-Report? Using Item Response Theory Calibration to Estimate Equable Scale Scores.

Blakey et al. (in preparation). Estimating interview-calibrated PTSD severity from self-report data using calibrated projection

Hien, D.A., et al. (in preparation). A cross-lagged analysis of PTSD change and its impact on SUD in a PTSD-SUD meta-analysis with individual patient data

Hien, D,A., et al. (in preparation). Updated systematic review and meta-analysis of individual patient data

​Hien, D.A., et al. (in preparation). The Consortium on Addictions, Stress and Trauma. Project Harmony 2.0: Advancing patient-centered research using meta-analysis of individual patient data to identify clinically significant trajectories of PTSD/SUD and recovery
outcomes: Protocol for an updated and expanded individual patient data metaanalysis and virtual clinical trial of treatments for comorbid PTSD and substance use disorders.

Lopez-Castro, T., et al. (in preparation) Interpersonal Violence and Substance Use Disorders Systematic Review.

Morgan-Lopez et al. (in preparation). Cumulative Average Treatment Effect (CATE) models for when intent-to-treat (ITT) analysis fails

Morgan-Lopez et al. (in preparation). PH2.0 Who gets better and who gets worse? Estimating clinically significant change 

Morgan-López, et al. (in preparation). Advancing PTSD–SUD treatment research through FAIR and FACT frameworks

Prakash, K., et al. (in preparation). “Impaired but Now Diagnosable?” A Framework for Incorporating Differential Symptom Weighting in the Empirical Classification of Full and Subthreshold PTSD.

Saavedra, L.M., et al. (in preparation) Baseline Depression Comorbidity Moderation of Treatment Effects: VCT Sample.

Saavedra et al. (in preparation). CSC conceptual paper

Saavedra et al. (in preperation). Recovery Capital
​
Saraiya, T.C., et al. (in preparation) Intervention Outcomes for Individuals with Posttraumatic Stress Disorder and Opioid Use Disorder: Comparison of Trauma-Focused and Non-Trauma-Focused Interventions

Saraiya, T., et al. (in preparation) Gender/sex as a moderator of PTSD and SUD treatments

Swarbrick, P., et al. (in preparation). Scoping review of recovery capital among individuals with co-occurring SUD and PTSD
NIAAA-funded R01​ (MPIs: Hien & Morgan-Lopez): 1 R01 AA025853
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